Two children were rushed to the hospital with life-threatening injuries after a Howard County police vehicle made a U-turn into the path of their vehicle in Anne Arundel County on Saturday.

Anne Arundel police say an on-duty Howard County officer was driving through an unfamiliar area when he made an illegal U-turn over a grass median into the path of a Honda traveling in the fast lane. Driver Jamie Marie Butler, 31, and passenger Charlie Norfolk, 34, both of Brooklyn Park, were taken to Johns Hopkins Trauma Center and treated for non-life threatening injuries.

Two children aged 11 and four were taken to Johns Hopkins Pediatric Trauma Center with life threatening injuries. Police are not releasing the children's names and it was unclear Sunday evening what condition the children were in.

Anne Arundel police say the initial investigation indicated driver error caused the crash. The investigation is ongoing.