A new Quinnipiac University poll showing Hillary Clinton handily beating Marco Rubio, Paul Ryan and Chris Christie in a hypothetical 2016 race has been generating buzz.

There’s no doubt that if Clinton chose to run, she’d be a prohibitive favorite to win the Democratic nomination given that there won’t be another phenomenon equal to President Obama in 2008. And she’d be a formidable adversary against any Republican.

But it’s also important to keep in mind that Clinton, despite going into 2008 with a tremendous advantage, had a lot of problematic moments as a candidate. Even if she’s broadly popular now, that could change when she moves back into daily campaign mode.

Also, her chances will largely hinge on how Obama’s second term goes. If the economy improves and his presidency is popular when the next election rolls around, it would obviously bolster her chances. But if he’s weighed down, as second term presidents often are, Americans will likely be looking for a new face in 2016.