Bill Nye is not a fan of several staffing picks made by the Trump administration and widespread de-regulation.

In particular, the science educator takes issue with EPA Administrator Scott Pruitt and Education Secretary Betsy DeVos, who he characterized as "the least qualified people on the planet to run" their respective agencies.

"There is a technique of dismantling government from within," Nye told the Guardian, attributing this way of thinking to White House chief strategist Steve Bannon.

Pruitt has received backlash for suggesting that carbon dioxide emissions are not to blame for global warming — which is the consensus among most climate scientists. He also made a name for himself as an Oklahoma attorney general who repeatedly spearheaded legal action against former President Barack Obama's EPA. Meanwhile DeVos has been criticized for her lack of experience in education policy, as noted by Sen. Elizabeth Warren during the confirmation process.

Nye, who became a household name in the 1990s with his popular show "Bill Nye the Science Guy," will be helping to lead Saturday's March for Science in Washington, D.C., as the event's honorary co-chair. He is expected to speak at the event. Similar marches are taking place across the world.

Nye characterized the state of science as being in a "dangerous place right now."

"Science has always been political but we don't want science to be partisan," he said. "Objective truths have become set aside and diminished and lawmakers are acting like a strong belief in something is as valid as careful peer review."

"The arbitrary nature of the cuts are worrying," Nye added. "When they say they are going to cut one regulation for every two, where do they get that number? Are we going to start driving on the other side of the street and not regulate air traffic?"

Trump's proposed budget released earlier this month includes deep cuts to science-related agencies including the National Institutes of Health (by about 20 percent or $5.8 billion) and Energy Department's Office of Science (also about 20 percent or $900 million). The budget process now moves to Congress, who will write up appropriations bills which will eventually be given to the president to be signed.