The poor relationship between the United States and Russia is atop the Kremlin’s list of disappointments in 2017.

“Russian-American relations and the position Washington takes toward our country can’t but elicit regret,” Kremlin spokesman Dmitry Peskov told a conference call of international reporters Friday, saying the worsening ties between the U.S. and Russia are “certainly” on the list of biggest disappointments.

Peskov blamed “anti-Russia hysteria” in Washington, but also admitted that “it takes two to tango.”

Russia wants good relations with the U.S. based on “mutual trust and mutual respect,” Peskov said.

When asked about President Trump's remarks to the New York Times about special counsel Robert Mueller’s ongoing investigation into Russian meddling in the 2016 presidential election, Peskov said the Kremlin is “still perplexed.”

"We have repeatedly stated our opinion on the anti-Russian hysteria that is fomented and maintained in the U.S. We are still perplexed in connection with all ongoing investigations," Peskov responded. "This, of course, is an internal affair of the United States, but in this case, of course, this is damaging our bilateral relations, and we regret this."

Russian President Vladimir Putin has denied his country meddled in last year's campaign, despite a report from the Office of the Director of National Intelligence that concludes with “high confidence” that “Russian President Vladimir Putin ordered an influence campaign in 2016 aimed at the U.S. presidential election.”

Trump has continually said there was no collusion between his campaign and Russia, and told the New York Times on Thursday that Mueller’s investigation makes the U.S. “look very bad.”

In the interview, Trump said there was “no collusion” 16 times during the 30-minute interview, and said he believes Mueller would treat him fairly.

The remarks from the Kremlin come a day after Secretary of State Rex Tillerson wrote the two countries have a “poor relationship.”

"On Russia, we have no illusions about the regime we are dealing with," Tillerson wrote in a New York Times op-ed. "The United States today has a poor relationship with a resurgent Russia that has invaded its neighbors Georgia and Ukraine in the last decade and undermined the sovereignty of Western nations by meddling in our election and others."

In November, Trump said on Twitter that having a positive relationship with Russia is “a good thing” and that the country can “greatly help” solve crisis nationwide, including terrorism.