North Korea warned Tuesday that the U.S. will be destroyed if it chooses to defy the "military giant" led by leader Kim Jong Un.

"In case the U.S. opts for confrontation and war at last, defying the strategic position of the DPRK, nuclear power of Juche and a world military giant, it will meet horrible nuclear strike and miserable and final ruin," the regime warned through North Korea's state-owned Central News Agency.

North Korea indicated its comment was a response to new sanctions the Trump administration pushed for and won in the United Nations.

"The U.S. cooked up another 'sanctions resolution' at the United Nations Security Council as part of its unprecedented military threat and sanctions and blockade to stifle the DPRK," the statement said. "The U.S. describes the DPRK's nuclear deterrence for self-defense as the 'biggest threat to peace,' but it is no more than a shameful logic and a brigandish deed to justify its crimes against peace on the Korean Peninsula."

The statement called the new UN sanctions "ridiculous" and said the regime is "not afraid of any sanctions, pressure and war."

"It is now in full readiness to destroy the enemies' bases with its resolute and preemptive strike if they show any slight sign of provocation," North Korea said through the Central News Agency.

President Trump taunted North Korean leader Kim Jong Un at the United Nations on Tuesday, during his first address to the international body. Trump said the U.S. would have "no choice but to totally destroy North Korea" if that country threatened the U.S. or its allies.

"Rocket Man is on a suicide mission for himself and his regime," Trump added, repeating his nickname for Kim.

North Korea hadn't responded to Trump as of late Tuesday night eastern standard time.