President Obama on Friday offered a staunch defense of his agenda in a fiery speech to the Democratic National Committee winter meeting, where he said Republicans were "0 for 2" in trying to turn back his agenda.

Obama, rallying the party faithful ahead of November's crucial midterm elections, urged Democrats to make Republicans go “0 for 3.”

“The top Republican in the Senate said his top priority wasn't to create jobs or expand opportunity, but to beat me,” said Obama. “So let's look at the scorecard. They're 0 for 2. This November, let's make them 0 for 3.”

In the speech, the president defended his health care reform law, which has Democrats worried after the rocky rollout of new insurance exchanges weakened public support for Obamacare.

The GOP has vowed to make the health law a central issue in November, and House Republicans have voted numerous times to repeal or block elements of the law.

“Republicans in Congress have been obsessed with one thing above all else,” said Obama, jokingly adding “no, not Ted Nugent” — a jab at the rocker who has been a vocal critic of his policies.

“They have been obsessed with repealing the Affordable Care Act. You know what they say: The 50th time is the charm,” said the president. “Maybe when you hit your 50th repeal vote you will win a prize. Maybe if you buy 50 repeal votes you get one free.

“We get you don't like it. I got it,” he continued, adding that Republicans had failed to offer a “serious plan of their own.”

“I'm sure it's coming any day now,” Obama said to laughter.

“Millions of Americans are more secure and will be more secure because of what we did,” said Obama of the Affordable Care Act.

“That's not something to repeal. That's something to celebrate. That's something to build on.”

The president’s speech also hammered home his “opportunity” agenda, which he's touted recently. Obama has vowed to make 2014 a “year of action” and to push his economic policies alone if Congress fails to act.

The president in recent weeks has signed a slew of executive orders and announced administration initiatives that don't require congressional action.

On Friday, he said those efforts had "gotten Republicans in Congress all stirred up."

"As if they preferred to do nothing," he added.

Obama said the coming midterms would set the tone for the nation’s economic future.

“The choice could not be clearer: opportunity for a few or opportunity for all,” he said. “That's what this election is about.”

The president also urged Democrats to turn out at the polls.

“When Democrats have everybody on the field, we cannot lose. That's just a fact,” he said.

“That's just the raw numbers. When Democrats vote, we win. There are more folks who believe in what we stand for than believe in what they stand for,” said Obama of the two parties.