Host Chris Wallace replayed a clip of Republican House Speaker John Boehner's outburst regarding the conservative groups earlier this week and asked Ryan to react.
"Look, I think John got his Irish up there," Ryan said, shrugging off Boehner's comments.
Ryan added that the groups were "part of our conservative family" even though they opposed their budget compromise with Democrats.
"I would prefer to keep these conversations within our family," he said. "John was frustrated because they came out against our agreement before we even reached an agreement. I was frustrated with that as well."
Ryan added that the Tea Party was "indispensable" and "invaluable" to the Republican party and keeping Washington accountable.