Republican Sen. Rand Paul will speak Tuesday night shortly after President Obama addresses the nation on the United States' escalating involvement in war-torn Syria.

A staunch opponent of U.S. intervention in the Syrian civil war, the Kentucky Republican is scheduled to respond to Obama's remarks and make the case against a military strike at 10 p.m.

Much remains in flux and it is not clear what the president will say to the American people in his evening remarks. While he initially was looking to make the case for use of military force in Syria following the use of chemical weapons by Syrian President Bashar Assad against rebels, a diplomatic option is gaining traction. Under that scenario, the U.S. would hold off on an attack if the Assad regime handed control of its chemical weapons over to international control.

A public response by Paul could prove to be a dicey maneuver without a clear sign of what Obama will say.

Paul, known to be weighing a potential 2016 presidential bid, also provided the Tea Party response to Obama's State of the Union address earlier this year. His stance against military action in Syria appeals to his libertarian base and strikes a similar anti-intervention sentiment as his father, former Texas Congressman and presidential hopeful Ron Paul.

A release from Paul's office did not say whether the networks, which will air Obama's comments, will also show the Republican's remarks.