Safety Brandon Meriweather sprained two ligaments in his left knee and will miss two to four weeks, coach Mike Shanahan said.

Meriweather injured his knee in practice on Monday, hurting the medial collateral ligament and the posterior collateral ligament. Meriweather injured the same knee in the second preseason game vs. Chicago and missed the final two preseason games.

“He was fine until [Monday],” Shanahan said. “He was practicing 100 percent. It was a freak accident. …He feels more optimistic than that, but the doctors felt it would take time.”

Second-year DeJon Gomes said he took some reps with the starters in practice Wednesday, though he wasn’t sure yet if he would start. Reed Doughty is the other option.

Meanwhile, linebacker Brian Orakpo and left guard Kory Lichtensteiger both practiced in full. The only player who was limited, Shanahan said, was nose tackle Chris Baker (ankle).

Shanahan said they’ll use full pads in practice Thursday, when he’ll get a better chance to see what Lichtensteiger can do.

“If there’s no setback he has a good chance to play,” Shanahan said. “I can’t tell if he’ll play every snap. We’ll have to wait and see.”