Democratic Rep. Jacky Rosen announced Thursday she will challenge Nevada Sen. Dean Heller for his seat in the Senate.

"Now more than ever, Nevadans deserve a senator they can trust to be an independent voice standing up to President Trump, not his enabler," Rosen's campaign announcement said. "Sen. Heller might not sound like President Trump, but his voting record shows he supported Trump's agenda 100 percent of the time in his first 100 days."

Pro-Trump groups launched advertisements against Heller because of his opposition to the Senate GOP's healthcare bill. Heller announced he would vote no on the bill unless changes, such as keeping Medicaid expansion, are made.

Heller is considered one of the most vulnerable Republicans in the 2018 midterm elections.

In the 2016 election, former presidential candidate Hillary Clinton won Nevada by a 2.4 percent margin over Trump. Democratic Sen. Catherine Cortez Masto defeated Republican Joe Heck in 2016 by the same margin for the seat vacated by Harry Reid.

Rosen, a computer programmer, was elected to Heck's former congressional district in 2016, which includes suburban Las Vegas.

"As a woman who worked my way through college and came up through the ranks as a computer programmer, as a leader in my faith-based community, as a caregiver for my aging parents and in-laws and now a mother to my daughter, I can't stand by and watch while President Trump and Sen. Heller leave middle-class families stranded," Rosen said in her announcement.