The Republican Party as we know it is dead, GOP analyst and NBC News political contributor Nicole Wallace declared late Thursday evening.

Her remarks came immediately after billionaire businessman and GOP nominee Donald Trump concluded his acceptance speech at the Republican National Convention in Cleveland.

"The Republican Party that I worked for for two decades died in this room tonight," she said during an NBC News panel discussion.

"We are now represented as a party by a man who believes in protectionism, isolationism and nativism. And those were the forces that George W. Bush, and I believe John McCain too, were most worried about during their times as the leaders of the Republican Party," she added.

MSNBC's Chuck Todd interject for clarity's sake, and said, "Striking comment. You believe the party died tonight?"

"Well, the voters picked this guy. This is where the Republican Party is now. They now are attracted to those forces of isolationism and protectionism. But the party I was part of for two decades is dead," she responded.