Oprah Winfrey earned the rare opportunity to convert her media charisma into a monogrammed TV channel. Now she’s the one tasked with rescuing OWN, the Oprah Winfrey Network, after a disappointing first year. It’s a high-stakes, potentially ego-shattering challenge that could make the strongest woman or man flinch. But win or lose, Winfrey says she relishes the fight to turn OWN’s fortunes around.

“Yes, some mistakes were made. Who hasn’t made mistakes? The real beauty is you can say, ‘I learned from that,’ ” Winfrey said. “I don’t worry about failure. I worry about, ‘Did I do all I could do?’ ”