BOSTON (AP) — Harvard University announced Monday that its school of public health has received a record $350 million donation to support students and bolster research into major global health threats.

The gift, the largest single donation in the history of the university, came from a philanthropic foundation established by the family of T.H. Chan, a Hong Kong real estate developer who died in 1986. Harvard President Drew Faust called the donation “transformative” and said it will help tackle the “most urgent and intractable challenges” in the area of public health.