A U.S. Chamber of Commerce ad for Republican Sen. Kelly Ayotte touts her as a potential check on the White House, in a sign that the business group already sees an advantage as portraying her as a figure to oppose Hillary Clinton if she is elected president.

“America’s future is far from certain,” a narrator in the new 30-second ad published Friday says. “But no matter who the next president is, New Hampshire needs a strong voice in the U.S. Senate. That senator: Kelly Ayotte.”