A clinical trial has demonstrated adults with peanut allergies may be able to eat small doses if they undergo fecal transplants, a hospital announced Saturday.
Fecal microbiota transplanted out of nonallergic donors into allergic people who previously could only eat less than half a peanut before reacting resulted in adults who became resilient to two peanuts, Boston Children’s Hospital said.
“These results were very encouraging,” said Dr. Rima Rachid, the lead investigator and co-director of the Food Allergy Program at the hospital. “A single FMT led to a significant increase in the threshold of reactivity to peanut at both 1 month and 4 months after treatment, showing that the effect was prolonged. This study is offering hope that microbiome interventions may be effective in food allergy.”
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Intestinal bacteria are a critical part of the immune system, researchers said. The study’s samples came from OpenBiome, a nonprofit stool bank in Cambridge, Massachusetts.
The study included 15 participants between the ages of 18 and 33, with one participant gaining the ability to eat as many as four peanuts without a reaction.
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Approximately 32 million people have food allergies in the United States, according to the Asthma and Allergy Foundation of America.
