Officials from the Centers for Disease Control and Prevention on Friday recommended that people cease vaping until a lung disease epidemic related to vaping products is better understood and controlled.

As many as 450 vaping-related illnesses have been reported across 33 states, including three deaths in Indiana, Illinois, and Oregon. The death in Oregon has been attributed to a man buying marijuana from a dispensary, according to state officials. The CDC is also investigating a possible fourth death related to vaping.