The Senate will vote this week on a massive bipartisan bill that combines 70 different measures aimed at reducing addiction and drug overdose deaths from opioids such as heroin and prescription painkillers.

The vote on the bill, the Opioid Crisis Response Act, is a culmination of months of hearings and negotiations across five committees. Supporters hope that the legislation will help reduce death tolls from opioid overdoses, which early data show surpassed 40,000 people in 2017.