In its effort to stem the national opioid crisis, the Trump administration has issued a new regulation giving the Drug Enforcement Administration greater control over how many prescription opioids are manufactured each year.

The DEA already sets quotas for how many opioids a manufacturer can make in a given year. But the new regulation, finalized by the Department of Justice on Wednesday, allows the DEA to lower the quota for drugs that are found to be diverted for abuse in especially large quantities.