The Food and Drug Administration granted full approval to the Pfizer-BioNTech two-dose COVID-19 vaccine, a move the Biden administration is hoping will convince holdouts to get the shots.

“While this and other vaccines have met the FDA’s rigorous, scientific standards for emergency use authorization, as the first FDA-approved COVID-19 vaccine, the public can be very confident that this vaccine meets the high standards for safety, effectiveness, and manufacturing quality the FDA requires of an approved product,” said acting FDA Commissioner Janet Woodcock.