Senators pressed President Donald Trump’s nominees to handle major public health programs, asking whether they supported the vaccine skepticism of Health and Human Services Secretary Robert F. Kennedy Jr., as the upper chamber grows increasingly frustrated with the administration’s management of vaccine policies.

Dr. Erica Schwartz, the nominee to be the director of the Centers for Disease Control and Prevention, and Sean Kaufman, the nominee to lead the Administration for Strategic Preparedness, faced pointed questions from both Democrats and Republicans regarding vaccines, which have been deeply politicized since the COVID-19 pandemic.