The joint U.S.-Israeli attack on Iran in the morning hours of Feb. 28 sparked the largest regional war in the Middle East in decades and marked several historical milestones.

Operation Epic Fury is the largest U.S. campaign since its invasion of Iraq in 2003, and is poised to reshape the order in the Middle East for the near future. The U.S. and Israel have inflicted heavily lopsided casualties on the Iranians, with U.S. losses being six soldiers dead as of Friday, while Iran has lost thousands so far.